In this unit you will learn about the science behind homeopathy (the minimum dose, the Law of Similars, dynamisation of the substance), toxins (unnatural chemical toxins, exogenous and endogenous sources of toxins, emotional and energetic toxins, the importance of liver detoxification and eliminations), the basics of homotoxicology (the Extra Cellular Matrix or Ground Substance of Alfred Pischinger), Regulatory Systems and Feedback Systems, Bioregulatory Medicine, Three Pillars of Homotoxicology, Greater Defence System, Acidosis, Bystander Reaction, the 6 Phase Table or Disease Evolution Table and Scientific laws, the Extra Cellular Matrix and Ground Regulation System of Pischinger (components, functions and regulatory responses of the ECM, deposition of toxins in the ECM, inflammation), bioregulatory medicine, the three pillars of homotoxicology (drainage and detoxification, cell and organ support, immunomodulation), greater defence system (the Reticuloendothelial system, the HPA axis, the Neural Reflex System, detoxification by the liver, detoxification of the Matrix, the Mucous Membranes), acidosis, Immune Bystander Reaction theory, the 6-Phase Table or Disease Evolution Table (excretion/humoral phase, reaction/inflammation phase, deposition phase, impregnation phase, degeneration phase and dedifferentiation/neoplasm phase) and using simple homotoxicology remedies in practice (preparations and remedies used in homotoxicology – Traumeel, Lymphomyosot, Nux Vomica Homaccord, Berberis Homaccord, “The Detox Kit”, Engystol, Nervoheel and Neurexan). This symptom may occur due to chronic brain diseases such as structural or idiopathic epilepsy ( 2, 3). Positive changes were stated as a decrease in negative behavior in comparison to the status before treatment or if the owner reported a positive behavioral effect after LEV administration. Statistical analysis revealed significance for the occurrence of negative behavioral effects within the first 2 weeks of treatment in this subgroup ( p< 0.

The ongoing controversies over safety of drugs such as cerivastatin and rofecoxib have shown the limits of the extent to which patients are willing to accept side effects, whether immediate adverse effects or long-term risk for complications, from drugs.In nine dogs LEV was applied as add-on treatment to other AEDs for a median time of 45 months (range, 1–75 months).

In our non-inferiority analysis, the degrees of improvements were highly similar across the board for the 11 different variables assessed, and non-inferiority of Nervoheel N could be shown for all variables as well as their summary score. In the Nervoheel N group, 128 patients were examined at the interim examination and 134 patients were available for the final examination. However, within group 1, dogs are reported to develop more obvious behavioral changes in comparison to initial LEV treatment after an increase in LEV dosage.

The onset of the behavioral changes became noticeable in all four dogs within the first 2 weeks of LEV treatment.

Two of each of the following breeds: Wire-Haired Dachshund, Miniature Bull Terrier, Jack Russel Terrier, Labrador Retriever, Boxer, West Highland White Terrier, Rhodesian Ridgeback, Magyar Vizsla, German Shepherds, Yorkshire Terrier and one of the following breeds: Chihuahua, Dogo Argentino, Cao de Serra de Aires, Fox Terrier, French Bulldog, Istrian Bracke, Landseer, German Spitz, Continental Bulldog, German shorthaired pointer, Pomeranian, Perro de Agua espagnol, Sheep Poodle, English Setter, Entlebucher Mountain Dog, German Pinscher, Pyrenean Mountain Dog, Sheltie, Puggle, Miniature American Shepherd, Beagle and German Bracke. The hypothesis of this study is, that LEV treatment induces behavioral changes or causes an intensifying of pre-existing behavioral abnormalities in dogs with epileptic seizures. Ja Jūs esat grūtniece vai barojat bērnu ar krūti, ja domājat, ka Jums varētu būt grūtniecība vai plānojat grūtniecību, pirms šo zāļu lietošanas konsultējieties ar ārstu vai farmaceitu.As blood pressure may drop as a side effect, the medicine must be taken with caution in the case of low blood pressure. A non-inferiority analysis was carried out for: headache, heart palpitations, backache, indigestion, lack of appetite, mild sexual dysfunction, fatigue, listlessness, sleep disturbances, restlessness, lack of concentration; as well as for the summary score of all variables. Nervoheel N is indicated for the temporary relief of symptoms of stress, including restlessness, insomnia, nervous tension and stress due to premenstrual syndrome and menopause, as well as restlessness in children. Increased activity ( n = 4), more energy ( n = 4), calmer mood ( n = 3), higher tolerance to environmental stress ( n = 3), increased obedience ( n = 1), and a joyful mood ( n = 1) were reported positive changes ( Table 2).

In addition, the tolerability of Nervoheel N was rated as ‘excellent’ by significantly more patients than that of lorazepam for the 4-week duration of the trial. Good tolerability is a common characteristic of many CAM medications and may be one reason for their growing popularity as a reaction to perceived limitations of conventional treatments ( 22).Behavioral side effects are more likely to occur in cases of pre-existing behavioral problems in humans ( 12– 14). The choice of treatment in each individual case was at the physician's discretion, based on their judgment of the most suitable treatment for each individual patient.